Enhanced uric acid detection using functionalized multi-walled carbon nanotube/AgNi nanocomposites: A comparative study on screen-printed carbon electrode (SPCE) and fabric-based biosensors
In the development of biosensors, it is essential to have sensors that provide rapid responses, exhibit high sensitivity and selectivity, and are non-invasive, such as screen-printed carbon electrode-based biosensors. In this study, SPCE-based and fabric-based biosensors were fabricated by modifying...
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Elsevier
2024-12-01
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| Series: | Sensors and Actuators Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666053924000390 |
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| author | Yuan Alfinsyah Sihombing Uperianti Rizky Indah Sari Beni Rio Hermanto Murni Handayani Samuel Priyantoro Kusumocahyo Mokhamad Fakhrul Ulum Rikson Siburian Cepi Kurniawan Nuni Widiarti Yeni Wahyuni Hartati Isa Anshori |
| author_facet | Yuan Alfinsyah Sihombing Uperianti Rizky Indah Sari Beni Rio Hermanto Murni Handayani Samuel Priyantoro Kusumocahyo Mokhamad Fakhrul Ulum Rikson Siburian Cepi Kurniawan Nuni Widiarti Yeni Wahyuni Hartati Isa Anshori |
| author_sort | Yuan Alfinsyah Sihombing |
| collection | DOAJ |
| description | In the development of biosensors, it is essential to have sensors that provide rapid responses, exhibit high sensitivity and selectivity, and are non-invasive, such as screen-printed carbon electrode-based biosensors. In this study, SPCE-based and fabric-based biosensors were fabricated by modifying the working electrode (WE) surface using functionalized Multi-walled Carbon Nanotube/AgNi nanocomposites (f-MWCNT/AgNi) to enhance the biosensor's performance in detecting uric acid (UA). The successful synthesis of the f-MWCNT/AgNi nanomaterial was confirmed through UV–Vis, Raman, SEM–EDX, and XRD analyses. The f-MWCNT/AgNi nanomaterials were deposited on the WE surface using drop-casting. Subsequently, electrochemical characteristic tests and UA detection performance were conducted using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods. The DPV curves revealed sensitivities of 27.699 μA/mM and 4.638 μA/mM for SPCE-based and fabric-based electrodes, respectively. The limit of detection (LOD) values for UA detection were 0.024 and 0.017 mM, with linearity (R2) 0.997 and 0.999 observed within the linear ranges of 0.05–1.00 and 1.0–5.0 mM, respectively. Both biosensors exhibited strong selectivity for UA against other components, including ascorbic acid, glucose, lactic acid, and ethanol. Based on these parameter values, f-MWCNT/AgNi-modified SPCE and fabric-based electrodes can be promoted as biosensors for uric acid detection. |
| format | Article |
| id | doaj-art-00eabd02ad3e41248e8fcafd32afb41c |
| institution | Kabale University |
| issn | 2666-0539 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Sensors and Actuators Reports |
| spelling | doaj-art-00eabd02ad3e41248e8fcafd32afb41c2024-11-15T06:14:59ZengElsevierSensors and Actuators Reports2666-05392024-12-018100223Enhanced uric acid detection using functionalized multi-walled carbon nanotube/AgNi nanocomposites: A comparative study on screen-printed carbon electrode (SPCE) and fabric-based biosensorsYuan Alfinsyah Sihombing0 Uperianti1Rizky Indah Sari2Beni Rio Hermanto3Murni Handayani4Samuel Priyantoro Kusumocahyo5Mokhamad Fakhrul Ulum6Rikson Siburian7Cepi Kurniawan8Nuni Widiarti9Yeni Wahyuni Hartati10Isa Anshori11Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Jl. Bioteknologi No.1, Medan 20155, Indonesia; Department of Physics, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jl. Ganesha No. 10, Bandung 40132, IndonesiaLab-on-Chip Group, Biomedical Engineering Department, School of Electrical Engineering and Informatics, Institut Teknologi Bandung, Bandung 40132, IndonesiaLab-on-Chip Group, Biomedical Engineering Department, School of Electrical Engineering and Informatics, Institut Teknologi Bandung, Bandung 40132, IndonesiaLab-on-Chip Group, Biomedical Engineering Department, School of Electrical Engineering and Informatics, Institut Teknologi Bandung, Bandung 40132, IndonesiaResearch Center for Nanotechnology Systems, National Research and Innovation Agency (BRIN), Puspiptek Area, Tangerang Selatan, Banten 15314, Indonesia; Department of Chemical Engineering, Pamulang University (UNPAM), Pamulang, Tangerang Selatan, Banten 15417, IndonesiaDepartment of Chemical Engineering, Faculty of Life Sciences and Technology, Swiss German University, Tangerang 15143, IndonesiaSchool of Veterinary Medicine and Biomedical Sciences, IPB University (Bogor Agricultural University), Jalan Agathis Kampus IPB Dramaga, Bogor 16680, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan 20155, IndonesiaChemistry Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri Semarang, Semarang 50229, IndonesiaChemistry Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri Semarang, Semarang 50229, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Science, Padjadjaran University, Jatinangor, 45363, Indonesia; Corresponding author at: Department of Chemistry, Faculty of Mathematics and Natural Science, Padjadjaran University, Jatinangor, 45363, Indonesia.Lab-on-Chip Group, Biomedical Engineering Department, School of Electrical Engineering and Informatics, Institut Teknologi Bandung, Bandung 40132, Indonesia; Research Center for Nanosciences and Nanotechnology (RCNN), Bandung Institute of Technology, Bandung 40132, IndonesiaIn the development of biosensors, it is essential to have sensors that provide rapid responses, exhibit high sensitivity and selectivity, and are non-invasive, such as screen-printed carbon electrode-based biosensors. In this study, SPCE-based and fabric-based biosensors were fabricated by modifying the working electrode (WE) surface using functionalized Multi-walled Carbon Nanotube/AgNi nanocomposites (f-MWCNT/AgNi) to enhance the biosensor's performance in detecting uric acid (UA). The successful synthesis of the f-MWCNT/AgNi nanomaterial was confirmed through UV–Vis, Raman, SEM–EDX, and XRD analyses. The f-MWCNT/AgNi nanomaterials were deposited on the WE surface using drop-casting. Subsequently, electrochemical characteristic tests and UA detection performance were conducted using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods. The DPV curves revealed sensitivities of 27.699 μA/mM and 4.638 μA/mM for SPCE-based and fabric-based electrodes, respectively. The limit of detection (LOD) values for UA detection were 0.024 and 0.017 mM, with linearity (R2) 0.997 and 0.999 observed within the linear ranges of 0.05–1.00 and 1.0–5.0 mM, respectively. Both biosensors exhibited strong selectivity for UA against other components, including ascorbic acid, glucose, lactic acid, and ethanol. Based on these parameter values, f-MWCNT/AgNi-modified SPCE and fabric-based electrodes can be promoted as biosensors for uric acid detection.http://www.sciencedirect.com/science/article/pii/S2666053924000390SPCE-based biosensorFabric-based biosensorf-MWCNT/AgNi nanocompositesUric acidSensitivity and selectivity |
| spellingShingle | Yuan Alfinsyah Sihombing Uperianti Rizky Indah Sari Beni Rio Hermanto Murni Handayani Samuel Priyantoro Kusumocahyo Mokhamad Fakhrul Ulum Rikson Siburian Cepi Kurniawan Nuni Widiarti Yeni Wahyuni Hartati Isa Anshori Enhanced uric acid detection using functionalized multi-walled carbon nanotube/AgNi nanocomposites: A comparative study on screen-printed carbon electrode (SPCE) and fabric-based biosensors Sensors and Actuators Reports SPCE-based biosensor Fabric-based biosensor f-MWCNT/AgNi nanocomposites Uric acid Sensitivity and selectivity |
| title | Enhanced uric acid detection using functionalized multi-walled carbon nanotube/AgNi nanocomposites: A comparative study on screen-printed carbon electrode (SPCE) and fabric-based biosensors |
| title_full | Enhanced uric acid detection using functionalized multi-walled carbon nanotube/AgNi nanocomposites: A comparative study on screen-printed carbon electrode (SPCE) and fabric-based biosensors |
| title_fullStr | Enhanced uric acid detection using functionalized multi-walled carbon nanotube/AgNi nanocomposites: A comparative study on screen-printed carbon electrode (SPCE) and fabric-based biosensors |
| title_full_unstemmed | Enhanced uric acid detection using functionalized multi-walled carbon nanotube/AgNi nanocomposites: A comparative study on screen-printed carbon electrode (SPCE) and fabric-based biosensors |
| title_short | Enhanced uric acid detection using functionalized multi-walled carbon nanotube/AgNi nanocomposites: A comparative study on screen-printed carbon electrode (SPCE) and fabric-based biosensors |
| title_sort | enhanced uric acid detection using functionalized multi walled carbon nanotube agni nanocomposites a comparative study on screen printed carbon electrode spce and fabric based biosensors |
| topic | SPCE-based biosensor Fabric-based biosensor f-MWCNT/AgNi nanocomposites Uric acid Sensitivity and selectivity |
| url | http://www.sciencedirect.com/science/article/pii/S2666053924000390 |
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