Efficient DNA-Free Protoplast Gene Editing of Elite Winegrape Cultivars for the Generation of Clones With Reduced Downy Mildew Susceptibility

Conclusions: This study has demonstrated that a relatively simple and robust protoplast isolation, DNA-free protoplast transfection and plant regeneration workflow can be used to efficiently produce nontransgenic, diploid, edited clones with desired phenotypes of four elite winegrape cultivars, incl...

Full description

Saved in:
Bibliographic Details
Main Authors: Christine Böttcher, Debra McDavid, Angelica M. Jermakow, Patricia Iocco-Corena, Nayana Arunasiri, Suzanne M. Maffei, Paul K. Boss
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Australian Journal of Grape and Wine Research
Online Access:http://dx.doi.org/10.1155/ajgw/8867814
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849319219554942976
author Christine Böttcher
Debra McDavid
Angelica M. Jermakow
Patricia Iocco-Corena
Nayana Arunasiri
Suzanne M. Maffei
Paul K. Boss
author_facet Christine Böttcher
Debra McDavid
Angelica M. Jermakow
Patricia Iocco-Corena
Nayana Arunasiri
Suzanne M. Maffei
Paul K. Boss
author_sort Christine Böttcher
collection DOAJ
description Conclusions: This study has demonstrated that a relatively simple and robust protoplast isolation, DNA-free protoplast transfection and plant regeneration workflow can be used to efficiently produce nontransgenic, diploid, edited clones with desired phenotypes of four elite winegrape cultivars, including the highly recalcitrant Cabernet Sauvignon.
format Article
id doaj-art-00e8c44f12c240cbb5e195b68b0fcba4
institution Kabale University
issn 1755-0238
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Australian Journal of Grape and Wine Research
spelling doaj-art-00e8c44f12c240cbb5e195b68b0fcba42025-08-20T03:50:32ZengWileyAustralian Journal of Grape and Wine Research1755-02382025-01-01202510.1155/ajgw/8867814Efficient DNA-Free Protoplast Gene Editing of Elite Winegrape Cultivars for the Generation of Clones With Reduced Downy Mildew SusceptibilityChristine Böttcher0Debra McDavid1Angelica M. Jermakow2Patricia Iocco-Corena3Nayana Arunasiri4Suzanne M. Maffei5Paul K. Boss6Agriculture and FoodAgriculture and FoodAgriculture and FoodAgriculture and FoodAgriculture and FoodAgriculture and FoodAgriculture and FoodConclusions: This study has demonstrated that a relatively simple and robust protoplast isolation, DNA-free protoplast transfection and plant regeneration workflow can be used to efficiently produce nontransgenic, diploid, edited clones with desired phenotypes of four elite winegrape cultivars, including the highly recalcitrant Cabernet Sauvignon.http://dx.doi.org/10.1155/ajgw/8867814
spellingShingle Christine Böttcher
Debra McDavid
Angelica M. Jermakow
Patricia Iocco-Corena
Nayana Arunasiri
Suzanne M. Maffei
Paul K. Boss
Efficient DNA-Free Protoplast Gene Editing of Elite Winegrape Cultivars for the Generation of Clones With Reduced Downy Mildew Susceptibility
Australian Journal of Grape and Wine Research
title Efficient DNA-Free Protoplast Gene Editing of Elite Winegrape Cultivars for the Generation of Clones With Reduced Downy Mildew Susceptibility
title_full Efficient DNA-Free Protoplast Gene Editing of Elite Winegrape Cultivars for the Generation of Clones With Reduced Downy Mildew Susceptibility
title_fullStr Efficient DNA-Free Protoplast Gene Editing of Elite Winegrape Cultivars for the Generation of Clones With Reduced Downy Mildew Susceptibility
title_full_unstemmed Efficient DNA-Free Protoplast Gene Editing of Elite Winegrape Cultivars for the Generation of Clones With Reduced Downy Mildew Susceptibility
title_short Efficient DNA-Free Protoplast Gene Editing of Elite Winegrape Cultivars for the Generation of Clones With Reduced Downy Mildew Susceptibility
title_sort efficient dna free protoplast gene editing of elite winegrape cultivars for the generation of clones with reduced downy mildew susceptibility
url http://dx.doi.org/10.1155/ajgw/8867814
work_keys_str_mv AT christinebottcher efficientdnafreeprotoplastgeneeditingofelitewinegrapecultivarsforthegenerationofcloneswithreduceddownymildewsusceptibility
AT debramcdavid efficientdnafreeprotoplastgeneeditingofelitewinegrapecultivarsforthegenerationofcloneswithreduceddownymildewsusceptibility
AT angelicamjermakow efficientdnafreeprotoplastgeneeditingofelitewinegrapecultivarsforthegenerationofcloneswithreduceddownymildewsusceptibility
AT patriciaioccocorena efficientdnafreeprotoplastgeneeditingofelitewinegrapecultivarsforthegenerationofcloneswithreduceddownymildewsusceptibility
AT nayanaarunasiri efficientdnafreeprotoplastgeneeditingofelitewinegrapecultivarsforthegenerationofcloneswithreduceddownymildewsusceptibility
AT suzannemmaffei efficientdnafreeprotoplastgeneeditingofelitewinegrapecultivarsforthegenerationofcloneswithreduceddownymildewsusceptibility
AT paulkboss efficientdnafreeprotoplastgeneeditingofelitewinegrapecultivarsforthegenerationofcloneswithreduceddownymildewsusceptibility