‘One Stop’ Therapy has a Satisfying Performance on AF Patients with Interatrial Communication: Evidence from Pooled Clinical Experience
Background: Left atrial appendage closure (LAAC) has been reported to be a viable alternative to prevent thromboembolic events for atrial fibrillation (AF) patients. Interatrial communication closure, such as atrial septal defect (ASD) and patent foramen ovale (PFO) closure could...
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| Format: | Article |
| Language: | English |
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IMR Press
2025-04-01
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| Series: | Reviews in Cardiovascular Medicine |
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| Online Access: | https://www.imrpress.com/journal/RCM/26/4/10.31083/RCM26662 |
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| author | Zhi-Yuan Zhang Feng Li Chi Geng Yu-Qi Chen Si-Liang Peng Yao-Ting Zhang You Zhang Xiao-Song Gu Hui Li |
| author_facet | Zhi-Yuan Zhang Feng Li Chi Geng Yu-Qi Chen Si-Liang Peng Yao-Ting Zhang You Zhang Xiao-Song Gu Hui Li |
| author_sort | Zhi-Yuan Zhang |
| collection | DOAJ |
| description | Background: Left atrial appendage closure (LAAC) has been reported to be a viable alternative to prevent thromboembolic events for atrial fibrillation (AF) patients. Interatrial communication closure, such as atrial septal defect (ASD) and patent foramen ovale (PFO) closure could significantly decrease the occurrence of stroke. For AF patients with interatrial communication, the success rate as well as the long-term outcomes of ‘One stop’ closure remain elusive. Methods: Studies were systematically screened using online databases (including PubMed, Cochrane Library, Web of Science, Embase, China National Knowledge Infrastructure (CNKI) database, and WanFang database) from their establishment to 1st August 2024. We utilized a fixed-effect model to synthesize the success rate and the long-term outcomes. Subgroup analysis was performed to identify the potential confounders. Results: A total of 7 studies comprising 156 patients were included. ASD/PFO closure combined with LAAC showed a high degree of feasibility, with a success rate of 1.00 (95% CI: 0.99, 1.00; p < 0.001). Meanwhile, ‘One stop’ ASD/PFO closure combined with LAAC exhibited a high long-term safety and a low occurrence of complications. Moreover, subgroup analysis revealed that the bleeding event occurrence was relatively higher in the male proportion ≥50% subgroup and HAS-BLED score ≥3 subgroup, respectively. Conclusions: ASD/PFO closure combined with LAAC has a satisfying performance on AF patients with interatrial communication. The PROSPERO Registration: CRD42023462221, https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023462221. |
| format | Article |
| id | doaj-art-00ba8784a81743ce9074f0147d46b74c |
| institution | Kabale University |
| issn | 1530-6550 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj-art-00ba8784a81743ce9074f0147d46b74c2025-08-20T03:53:39ZengIMR PressReviews in Cardiovascular Medicine1530-65502025-04-012642666210.31083/RCM26662S1530-6550(24)01727-7‘One Stop’ Therapy has a Satisfying Performance on AF Patients with Interatrial Communication: Evidence from Pooled Clinical ExperienceZhi-Yuan Zhang0Feng Li1Chi Geng2Yu-Qi Chen3Si-Liang Peng4Yao-Ting Zhang5You Zhang6Xiao-Song Gu7Hui Li8Department of Cardiology, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, ChinaBackground: Left atrial appendage closure (LAAC) has been reported to be a viable alternative to prevent thromboembolic events for atrial fibrillation (AF) patients. Interatrial communication closure, such as atrial septal defect (ASD) and patent foramen ovale (PFO) closure could significantly decrease the occurrence of stroke. For AF patients with interatrial communication, the success rate as well as the long-term outcomes of ‘One stop’ closure remain elusive. Methods: Studies were systematically screened using online databases (including PubMed, Cochrane Library, Web of Science, Embase, China National Knowledge Infrastructure (CNKI) database, and WanFang database) from their establishment to 1st August 2024. We utilized a fixed-effect model to synthesize the success rate and the long-term outcomes. Subgroup analysis was performed to identify the potential confounders. Results: A total of 7 studies comprising 156 patients were included. ASD/PFO closure combined with LAAC showed a high degree of feasibility, with a success rate of 1.00 (95% CI: 0.99, 1.00; p < 0.001). Meanwhile, ‘One stop’ ASD/PFO closure combined with LAAC exhibited a high long-term safety and a low occurrence of complications. Moreover, subgroup analysis revealed that the bleeding event occurrence was relatively higher in the male proportion ≥50% subgroup and HAS-BLED score ≥3 subgroup, respectively. Conclusions: ASD/PFO closure combined with LAAC has a satisfying performance on AF patients with interatrial communication. The PROSPERO Registration: CRD42023462221, https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023462221.https://www.imrpress.com/journal/RCM/26/4/10.31083/RCM26662atrial fibrillationatrial septal defect closureasd closurepatent foramen ovale closurepfo closureleft atrial appendage closurelaac |
| spellingShingle | Zhi-Yuan Zhang Feng Li Chi Geng Yu-Qi Chen Si-Liang Peng Yao-Ting Zhang You Zhang Xiao-Song Gu Hui Li ‘One Stop’ Therapy has a Satisfying Performance on AF Patients with Interatrial Communication: Evidence from Pooled Clinical Experience Reviews in Cardiovascular Medicine atrial fibrillation atrial septal defect closure asd closure patent foramen ovale closure pfo closure left atrial appendage closure laac |
| title | ‘One Stop’ Therapy has a Satisfying Performance on AF Patients with Interatrial Communication: Evidence from Pooled Clinical Experience |
| title_full | ‘One Stop’ Therapy has a Satisfying Performance on AF Patients with Interatrial Communication: Evidence from Pooled Clinical Experience |
| title_fullStr | ‘One Stop’ Therapy has a Satisfying Performance on AF Patients with Interatrial Communication: Evidence from Pooled Clinical Experience |
| title_full_unstemmed | ‘One Stop’ Therapy has a Satisfying Performance on AF Patients with Interatrial Communication: Evidence from Pooled Clinical Experience |
| title_short | ‘One Stop’ Therapy has a Satisfying Performance on AF Patients with Interatrial Communication: Evidence from Pooled Clinical Experience |
| title_sort | one stop therapy has a satisfying performance on af patients with interatrial communication evidence from pooled clinical experience |
| topic | atrial fibrillation atrial septal defect closure asd closure patent foramen ovale closure pfo closure left atrial appendage closure laac |
| url | https://www.imrpress.com/journal/RCM/26/4/10.31083/RCM26662 |
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