Detection of fasting blood sugar using a microwave sensor and convolutional neural network

Abstract Monitoring of fasting blood sugar (FBS) is a critical component in the diagnosis and management of diabetes, one of the most widespread chronic diseases globally. Microwave sensing—particularly through microstrip-based sensors—has recently gained attention as a promising technique for blood...

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Main Authors: Mohammad Amir Sattari, Mohsen Hayati
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-06502-y
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author Mohammad Amir Sattari
Mohsen Hayati
author_facet Mohammad Amir Sattari
Mohsen Hayati
author_sort Mohammad Amir Sattari
collection DOAJ
description Abstract Monitoring of fasting blood sugar (FBS) is a critical component in the diagnosis and management of diabetes, one of the most widespread chronic diseases globally. Microwave sensing—particularly through microstrip-based sensors—has recently gained attention as a promising technique for blood glucose monitoring, offering advantages such as low cost, high sensitivity, real-time response capability, and suitability for compact and wearable systems. In this study, a miniaturized microstrip microwave sensor is presented for non-contact FBS detection. Blood samples were directly collected from 78 individuals and analyzed using a clinical-grade auto-chemistry analyzer to determine reference FBS levels. Each sample was measured five times on the microwave sensor, resulting in a total of 390 transmission responses (S21) across a frequency range of 30 kHz to 18 GHz. These responses were recorded under controlled laboratory conditions, ensuring consistency and minimizing environmental interference. To interpret the complex, non-linear features of the sensor response, a convolutional neural network (CNN) was developed and trained using the entire dataset. The network demonstrated highly promising performance in estimating FBS values, achieving a mean relative error (MRE) of 1.31%. The results confirm the feasibility of combining broadband microwave sensing with deep learning techniques to enable reliable non-contact blood glucose measurement. This approach holds strong potential for integration into future wearable health monitoring systems, providing more user-friendly diabetic management tools without the frequent use of conventional blood sampling techniques.
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spelling doaj-art-00875c442807442281b51a27a062db8d2025-08-20T03:03:24ZengNature PortfolioScientific Reports2045-23222025-07-0115111710.1038/s41598-025-06502-yDetection of fasting blood sugar using a microwave sensor and convolutional neural networkMohammad Amir Sattari0Mohsen Hayati1Electrical Engineering Department, Faculty of Engineering, Razi UniversityElectrical Engineering Department, Faculty of Engineering, Razi UniversityAbstract Monitoring of fasting blood sugar (FBS) is a critical component in the diagnosis and management of diabetes, one of the most widespread chronic diseases globally. Microwave sensing—particularly through microstrip-based sensors—has recently gained attention as a promising technique for blood glucose monitoring, offering advantages such as low cost, high sensitivity, real-time response capability, and suitability for compact and wearable systems. In this study, a miniaturized microstrip microwave sensor is presented for non-contact FBS detection. Blood samples were directly collected from 78 individuals and analyzed using a clinical-grade auto-chemistry analyzer to determine reference FBS levels. Each sample was measured five times on the microwave sensor, resulting in a total of 390 transmission responses (S21) across a frequency range of 30 kHz to 18 GHz. These responses were recorded under controlled laboratory conditions, ensuring consistency and minimizing environmental interference. To interpret the complex, non-linear features of the sensor response, a convolutional neural network (CNN) was developed and trained using the entire dataset. The network demonstrated highly promising performance in estimating FBS values, achieving a mean relative error (MRE) of 1.31%. The results confirm the feasibility of combining broadband microwave sensing with deep learning techniques to enable reliable non-contact blood glucose measurement. This approach holds strong potential for integration into future wearable health monitoring systems, providing more user-friendly diabetic management tools without the frequent use of conventional blood sampling techniques.https://doi.org/10.1038/s41598-025-06502-yMicrowave sensorMicrostripFasting blood sugarConvolutional neural networkDeep learningBiomedical sensing
spellingShingle Mohammad Amir Sattari
Mohsen Hayati
Detection of fasting blood sugar using a microwave sensor and convolutional neural network
Scientific Reports
Microwave sensor
Microstrip
Fasting blood sugar
Convolutional neural network
Deep learning
Biomedical sensing
title Detection of fasting blood sugar using a microwave sensor and convolutional neural network
title_full Detection of fasting blood sugar using a microwave sensor and convolutional neural network
title_fullStr Detection of fasting blood sugar using a microwave sensor and convolutional neural network
title_full_unstemmed Detection of fasting blood sugar using a microwave sensor and convolutional neural network
title_short Detection of fasting blood sugar using a microwave sensor and convolutional neural network
title_sort detection of fasting blood sugar using a microwave sensor and convolutional neural network
topic Microwave sensor
Microstrip
Fasting blood sugar
Convolutional neural network
Deep learning
Biomedical sensing
url https://doi.org/10.1038/s41598-025-06502-y
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AT mohsenhayati detectionoffastingbloodsugarusingamicrowavesensorandconvolutionalneuralnetwork