Label-free determination of diffusion coefficients at the nanoscale through modelling of the Surface Plasmon Resonance signal.

Label-free determination of diffusion coefficients at the nanoscale through modelling of the Surface Plasmon Resonance signal.

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Surface plasmon resonance (SPR) is normally used to measure the kinetic parameters of biomolecular interactions between a molecule immobilized on a gold surface and another one flowing in a microfluidic channel above the surface. During the SPR measurements, convection-diffusion phenomena occur insi...

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Bibliographic Details
Main Authors: Gabriele Antonio Zingale, Irene Pandino, Damiano Calcagno, Maria Luisa Perina, Nunzio Tuccitto, Giuseppe Grasso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0312594
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