Adaptive randomised controlled non-inferiority multicentre trial (the Ketodex Trial) on intranasal dexmedetomidine plus ketamine for procedural sedation in children: study protocol by Martin Offringa, Samina Ali, Naveen Poonai, Serena Hickes, Petros Pechlivanoglou, Quynh Doan, Darcy Beer, Terry Klassen, Maryna Yaskina, Anna Heath, Scott Sawyer, Maala Bhatt, Vikram Sabhaney, Kamary Coriolano, April Kam

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Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (the PROMIZING study): update to the statistical analysis plan for a randomized controlled tri... by Karen J. Bosma, Myriam Lafreniere-Roula, Arlene Jiang, Anna Heath, Yongdong Ouyang, Kaitlyn Wade, Pingzhao Hu, Karen E. A. Burns, Claudio M. Martin, Yoanna Skrobik, Sorcha Mulligan, Kevin E. Thorpe, Laurent Brochard, members of the Canadian Critical Care Trials Group and the REVA Network

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